1481-1486 Musial LAJP 2561:Musial
نویسنده
چکیده
The deposition of chlorhexidine base on thermosensitive N-isopropylacrylamide polymeric microparticles was assessed in this study using energy dispersive X-ray spectrometry (EDXS) in scanning electron microscopy (SEM) setting. Three different types of polymer were synthesized. The PN1 was a polymer with terminal anionic groups resulting from potassium persulphate initiator. The PN2 was synthesized with 2,2’-azobis(2-methylpropionamidine)dihydrochloride, what resulted in cationic amidine terminal groups. The PN3 had anionic terminals, however increased hydrophobicity was maintained with Ntert-butylacrylate functional groups. The thermosensitivity of the polymer-chlorhexidine complexes was confirmed by the turbidimetric assay. The deposition patterns, observed in/on the polymers give the assumption to develop the applications of evaluated polymers as factors influencing chlorhexidine release from the topical formulations.
منابع مشابه
Social Network Analysis in Applications
Katarzyna Musial a,∗, Piotr Brodka b and Matteo Magnani c a Faculty of Science and Technology, Data Science Institute, Bournemouth University, Bournemouth, UK E-mail: [email protected] b Department of Computational Intelligence, Wroclaw University of Technology, Wroclaw, Poland E-mail: [email protected] c Department of Information Technology, Uppsala University, Uppsala, Swe...
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